RESTYLANE
 What is
RESTYLANE?
RESTYLANE is a gel that is injected into the skin in order
to add volume to lips and lift up wrinkles and folds.
 RESTYLANE consists of hyaluronic acid, which is a natural substance already present in
your body. Once in the skin, RESTYLANE works by creating volume and fullness.
 The hyaluronic acid in RESTYLANE is
non-animal, which virtually eliminates any risk of animal based disease or allergic reaction.
BEFORE
TREATMENT AFTER
TREATMENT

How is a treatment
performed?
RESTYLANE comes in a 1ml syringe. During treatment, the crystal-clear RESTYLANE gel
is injected into the skin in tiny amounts with a very fine needle. The gel produces volume under the wrinkle by
attracting and holding water molecules in your body. The wrinkle or depression is lifted up and smoothed
out. When enhancing lips or facial contours, RESTYLANE adds volume and shape to the treated area with a smooth,
natural look.
How long will the treatment session
take?
Treatment with RESTYLANE is a very quick and easy process. As no pre-test is needed,
the treatment can be carried out immediately. A treatment generally takes 15 to 30 minutes. The time differs
somewhat, depending on the correction you wish to have performed.
What can be treated?
RESTYLANE can be used for smoothing out folds and wrinkles, lip enhancements and
shaping facial contours, including under the eyes. The most common areas are the nasolabial folds (from the root of
the nose to the angle of the mouth) and the lips, although other areas can also be treated. Very superficial
wrinkles may be difficult to correct with RESTYLANE. Very deep wrinkles may require more than one syringe to
correct.
Does it hurt?
Most people find the injections relatively painless, however, there may be some
discomfort. If you like, a topical anesthetic can be applied to the area being treated prior to your procedure.
When enhancing the lips, a local anesthetic injection (dental block) is often given.
How soon will I see the
results?
The results can be seen immediately and continue to improve over the next 1 to 2
weeks.
What will I look like after the
treatment?
Immediately after the treatment, you can expect slight redness, swelling, tenderness
or an itching sensation in the treated area.
This is a normal result of the injection. The discomfort is temporary and generally
disappears in a few days. After a lip treatment, the lips may become swollen and look somewhat uneven. This can
persist for a few days (up to a week). If the discomfort continues, please contact your
physician.
What should I bear in mind after my
treatment with RESTYLANE?
During the first 48 hours after your treatment, do not massage or rub the treated
area. If you have had a lip enhancement, avoid puckering your lips for the first two days after the treatment.
Until the initial swelling and redness have resolved, do not expose the treated area to intense heat (e.g. in a
solarium or by sunbathing) or extreme cold.
Can RESTYLANE replace surgical
procedures?
No. However, RESTYLANE is sometimes used in conjunction with surgery to fill out
wrinkles that cannot be removed by surgery.
What should I think about before I have
a RESTYLANE treatment?
Look at yourself in the mirror and think about the result you are
expecting.
Try to convey your expectations to your physician before the treatment and ask them what can be done to achieve the
results you expect.
Do I need to have a skin
test?
No skin test is required.
Are there any
side-effects?
The rate of reactions to RESTYLANE is very low. However, after the treatment some
common injection-related reactions may occur, such as swelling, redness, pain, itching, discoloration and
tenderness at the injection site. These typically resolve spontaneously within a few days after injection into the
skin and within a week after the injection into the lips. Other types of reactions are very rare, but about 1 in
2000 treated patients have experienced localized reactions thought to be of a hypersensitive nature. These have
usually consisted of swelling at the injection site, sometimes affecting the surrounding tissues.
Redness, tenderness and rarely acne-like formations have also been
reported.
These reactions have either started a few days after the injection or after a delay
of two to four weeks, and have generally been described as mild to moderate and self-limiting with an average
duration of two weeks. This text does not contain all the information known about these products. For more
information please consult your practitioner.
Can patients with allergies of different
kinds be more sensitive to RESTYLANE?
So far, no connection between patients with allergies and patients that report a
reaction to RESTYLANE has been established.
How long does the effect of a RESTYLANE treatment last?
The length of time the effect of a RESTYLANE treatment lasts is very individual and
depends on many factors, such as the structure of your skin, lifestyle, age, the degree of perfection demanded and
the injection technique of the practitioner.
Experience indicates that touch-up and follow-up treatments will add to the duration.
Most people choose to have a new treatment within 6 to 8 months after the initial treatment.
Does RESTYLANE get stiffer in cold
weather? What happens in the sun?
You should not expose the treated area to intense heat (e.g. in a solarium or by
sunbathing) or extreme cold for the first few days after the treatment in order to avoid the risk of inflammation
as the area has been disturbed. However, once RESTYLANE has integrated into the body, it will adjust to your normal
body temperature.
How will my skin look without follow-up
treatments?
The correction will gradually disappear until your skin looks like it did before the
treatment. Follow-up injections will help you maintain your correction.
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