RESTYLANE
 What is
RESTYLANE?
RESTYLANE is a gel that is injected
into the skin in order to add volume to lips and
lift up wrinkles and
folds.
 RESTYLANE consists of hyaluronic acid,
which is a natural substance already present in
your body. Once in the skin, RESTYLANE works by
creating volume and fullness.
 The hyaluronic
acid in RESTYLANE is non-animal, which virtually
eliminates any risk of animal based disease or allergic
reaction.
BEFORE
TREATMENT AFTER
TREATMENT

How is a treatment
performed?
RESTYLANE comes in a 1ml syringe.
During treatment, the crystal-clear RESTYLANE gel is injected
into the skin in tiny amounts with a very fine needle. The gel
produces volume under the wrinkle by attracting and holding
water molecules in your body. The wrinkle or
depression is lifted up and smoothed out. When enhancing
lips or facial contours, RESTYLANE adds volume and shape to the
treated area with a smooth, natural
look.
How long will the treatment session
take?
Treatment with RESTYLANE is a
very quick and easy process. As no pre-test is needed, the
treatment can be carried out immediately. A treatment generally
takes 15 to 30 minutes. The time differs somewhat, depending on
the correction you wish to have performed.
What can be treated?
RESTYLANE can be used for
smoothing out folds and wrinkles, lip enhancements and shaping
facial contours, including under the eyes. The most common
areas are the nasolabial folds (from the root of the nose to
the angle of the mouth) and the lips, although other areas
can also be treated. Very superficial wrinkles may be difficult
to correct with RESTYLANE. Very deep wrinkles may require more
than one syringe to correct.
Does it hurt?
Most people find the injections
relatively painless, however, there may be some
discomfort. If you like, a topical anesthetic can be applied to
the area being treated prior to your procedure. When enhancing
the lips, a local anesthetic injection (dental block) is
often given.
How soon will I see the
results?
The results can be seen
immediately and continue to improve over the next 1 to 2
weeks.
What will I look like after the
treatment?
Immediately after the treatment,
you can expect slight redness, swelling, tenderness or an
itching sensation in the treated area.
This is a normal result of the
injection. The discomfort is temporary and generally disappears
in a few days. After a lip treatment, the lips may become
swollen and look somewhat uneven. This can persist for a few
days (up to a week). If the discomfort continues, please
contact your physician.
What should I bear in mind after my treatment
with RESTYLANE?
During the first 48 hours after
your treatment, do not massage or rub the treated area. If you
have had a lip enhancement, avoid puckering your lips for the
first two days after the treatment. Until the initial swelling
and redness have resolved, do not expose the treated area to
intense heat (e.g. in a solarium or by sunbathing) or extreme
cold.
Can RESTYLANE replace surgical
procedures?
No. However, RESTYLANE is
sometimes used in conjunction with surgery to fill out wrinkles
that cannot be removed by surgery.
What should I think about before I have a
RESTYLANE treatment?
Look at
yourself in the mirror and think about the result you are
expecting.
Try to convey your expectations to your physician before the
treatment and ask them what can be done to achieve the results
you expect.
Do I need to have a skin
test?
No skin test is
required.
Are there any
side-effects?
The rate of reactions to
RESTYLANE is very low. However, after the treatment some common
injection-related reactions may occur, such as swelling,
redness, pain, itching, discoloration and tenderness at the
injection site. These typically resolve spontaneously within a
few days after injection into the skin and within a week after
the injection into the lips. Other types of reactions are very
rare, but about 1 in 2000 treated patients have experienced
localized reactions thought to be of a hypersensitive nature.
These have usually consisted of swelling at the injection site,
sometimes affecting the surrounding tissues.
Redness, tenderness and rarely
acne-like formations have also been reported.
These reactions have either
started a few days after the injection or after a delay of two
to four weeks, and have generally been described as mild to
moderate and self-limiting with an average duration of two
weeks. This text does not contain all the information known
about these products. For more information please consult your
practitioner.
Can patients with allergies of different
kinds be more sensitive to RESTYLANE?
So far, no connection between
patients with allergies and patients that report a reaction to
RESTYLANE has been established.
How long does the effect
of a RESTYLANE treatment last?
The length of time the effect of
a RESTYLANE treatment lasts is very individual and depends on
many factors, such as the structure of your skin, lifestyle,
age, the degree of perfection demanded and the injection
technique of the practitioner.
Experience indicates that
touch-up and follow-up treatments will add to the duration.
Most people choose to have a new treatment within 6 to 8 months
after the initial treatment.
Does RESTYLANE get stiffer in cold weather?
What happens in the sun?
You should not expose the treated
area to intense heat (e.g. in a solarium or by sunbathing) or
extreme cold for the first few days after the treatment in
order to avoid the risk of inflammation as the area has been
disturbed. However, once RESTYLANE has integrated into the
body, it will adjust to your normal body
temperature.
How will my skin look without follow-up
treatments?
The correction will gradually
disappear until your skin looks like it did before the
treatment. Follow-up injections will help you maintain your
correction.
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